Bioconductor Single Package Builder - Build History

Snapshot Date: 
URL:  https://git.bioconductor.org/packages/methodical
Last Changed Rev:  / Revision: 
Last Changed Date: 

Hostname OS /Arch BUILD CHECK BUILD BIN POST-PROCESSING
nebbiolo2 Linux (Ubuntu 22.04.2 LTS)/x86_64   OK     ERROR     skipped     OK  
lconway macOS 12.6.5 Monterey/x86_64   OK     ERROR     OK     OK  

nebbiolo2 Summary

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Package: methodical
Version: 0.99.0
RVersion: 4.3
BiocVersion: 3.18
BuildCommand: /home/biocbuild/bbs-3.18-bioc/R/bin/R CMD build --keep-empty-dirs --no-resave-data methodical
BuildTime: 0 minutes 52.86 seconds
CheckCommand: BiocCheckGitClone('methodical') && /home/biocbuild/bbs-3.18-bioc/R/bin/R CMD check --no-vignettes --timings --library=/home/pkgbuild/packagebuilder/workers/jobs/3169/R-libs --install=check:/home/pkgbuild/packagebuilder/workers/jobs/3169/methodical_20231006145408/methodical.install-out.txt methodical_0.99.0.tar.gz && BiocCheck('methodical_0.99.0.tar.gz', `new-package`=TRUE)
CheckTime: 5 minutes 48.58 seconds
BuildBinCommand:
BuildBinTime:
PackageFileSize: 7095.97 KiB
BuildID:: methodical_20231006145408
PreProcessing: Starting Git clone. Installing dependencies. Checking Git Clone. Installing package: methodical. Starting Build package. Starting Check package.
PostProcessing: Finished Git clone. Package type: Software. Installing dependency status: 0. Checking git clone status: 0. Installing package status: 0. Build Package status: 0. Adding Build Product Information to Database.Checking Package status: 1.

nebbiolo2 BUILD SRC output

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===============================

 R CMD BUILD

===============================

* checking for file ‘methodical/DESCRIPTION’ ... OK
* preparing ‘methodical’:
* checking DESCRIPTION meta-information ... OK
* installing the package to build vignettes
* creating vignettes ... OK
* checking for LF line-endings in source and make files and shell scripts
* checking for empty or unneeded directories
* looking to see if a ‘data/datalist’ file should be added
  NB: this package now depends on R (>= 3.5.0)
  WARNING: Added dependency on R >= 3.5.0 because serialized objects in
  serialize/load version 3 cannot be read in older versions of R.
  File(s) containing such objects:
    ‘methodical/inst/extdata/tubb6_meth_rse/se.rds’
* building ‘methodical_0.99.0.tar.gz’


nebbiolo2 CHECK output

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===============================

 BiocCheckGitClone('methodical')

===============================

─ BiocCheckVersion: 1.37.16
─ BiocVersion: 3.18
─ Package: methodical
─ PackageVersion: 0.99.0
─ sourceDir: /home/pkgbuild/packagebuilder/workers/jobs/3169/methodical_20231006145408/methodical
─ platform: unix
─ isTarBall: FALSE

* Checking valid files...
* Checking for stray BiocCheck output folders...
* Checking for inst/doc folders...
* Checking DESCRIPTION...
* Checking if DESCRIPTION is well formatted...
* Checking for valid maintainer...
* Checking CITATION...

─ BiocCheck results ──
0 ERRORS | 0 WARNINGS | 0 NOTES

For more details, run
    browseVignettes(package = 'BiocCheck')




===============================

 R CMD CHECK

===============================

* using log directory ‘/home/pkgbuild/packagebuilder/workers/jobs/3169/methodical_20231006145408/methodical.Rcheck’
* using R version 4.3.1 (2023-06-16)
* using platform: x86_64-pc-linux-gnu (64-bit)
* R was compiled by
    gcc (Ubuntu 11.3.0-1ubuntu1~22.04.1) 11.3.0
    GNU Fortran (Ubuntu 11.3.0-1ubuntu1~22.04.1) 11.3.0
* running under: Ubuntu 22.04.3 LTS
* using session charset: UTF-8
* using option ‘--no-vignettes’
* checking for file ‘methodical/DESCRIPTION’ ... OK
* this is package ‘methodical’ version ‘0.99.0’
* package encoding: UTF-8
* checking package namespace information ... OK
* checking package dependencies ... OK
* checking if this is a source package ... OK
* checking if there is a namespace ... OK
* checking for hidden files and directories ... OK
* checking for portable file names ... OK
* checking for sufficient/correct file permissions ... OK
* checking whether package ‘methodical’ can be installed ... OK
* checking installed package size ... OK
* checking package directory ... OK
* checking for future file timestamps ... OK
* checking ‘build’ directory ... OK
* checking DESCRIPTION meta-information ... OK
* checking top-level files ... OK
* checking for left-over files ... OK
* checking index information ... OK
* checking package subdirectories ... OK
* checking R files for non-ASCII characters ... OK
* checking R files for syntax errors ... OK
* checking whether the package can be loaded ... [6s/6s] OK
* checking whether the package can be loaded with stated dependencies ... [6s/6s] OK
* checking whether the package can be unloaded cleanly ... [6s/6s] OK
* checking whether the namespace can be loaded with stated dependencies ... [6s/6s] OK
* checking whether the namespace can be unloaded cleanly ... [6s/6s] OK
* checking loading without being on the library search path ... [6s/6s] OK
* checking use of S3 registration ... OK
* checking dependencies in R code ... NOTE
Unexported object imported by a ':::' call: ‘HDF5Array:::.serialize_HDF5SummarizedExperiment’
  See the note in ?`:::` about the use of this operator.
* checking S3 generic/method consistency ... OK
* checking replacement functions ... OK
* checking foreign function calls ... OK
* checking R code for possible problems ... [22s/22s] NOTE
annotate_granges: no visible global function definition for ‘is’
annotate_meth_site_plot: no visible global function definition for
  ‘subsetByOverlaps’
annotate_meth_site_plot: no visible global function definition for
  ‘setNames’
annotate_meth_site_plot: no visible global function definition for
  ‘colorRampPalette’
annotate_meth_site_plot: no visible binding for global variable
  ‘region_type’
calculate_meth_site_transcript_cors: no visible global function
  definition for ‘%do%’
calculate_meth_site_transcript_cors: no visible binding for global
  variable ‘chunk’
calculate_meth_site_transcript_cors: no visible global function
  definition for ‘subsetByOverlaps’
calculate_meth_site_transcript_cors: no visible global function
  definition for ‘%dopar%’
calculate_meth_site_transcript_cors: no visible global function
  definition for ‘setNames’
calculate_meth_site_transcript_cors: no visible binding for global
  variable ‘transcript_name’
calculate_meth_site_transcript_cors: no visible binding for global
  variable ‘transcript_tss’
calculate_region_methylation_transcript_cors: no visible binding for
  global variable ‘transcript’
calculate_region_methylation_transcript_cors: no visible global
  function definition for ‘setNames’
calculate_region_methylation_transcript_cors: no visible global
  function definition for ‘p.adjust’
chunk_regions: no visible global function definition for
  ‘subsetByOverlaps’
create_meth_rse_from_hdf5: no visible global function definition for
  ‘setNames’
create_random_regions: no visible global function definition for
  ‘seqlengths’
create_random_regions: no visible global function definition for
  ‘overlapsAny’
expand_granges: no visible global function definition for ‘is’
expand_granges: no visible global function definition for ‘IRanges’
kallisto_quantify: no visible global function definition for ‘setNames’
mask_ranges_in_rse: no visible global function definition for ‘is’
mask_ranges_in_rse: no visible global function definition for
  ‘queryHits’
plot_meth_site_values: no visible global function definition for
  ‘seqlevels’
plot_meth_site_values: no visible global function definition for
  ‘complete.cases’
plot_meth_site_values: no visible binding for global variable
  ‘meth_site_plot_position’
plot_methodical_scores: no visible global function definition for
  ‘seqlevels’
plot_methodical_scores: no visible binding for global variable
  ‘meth_site_start’
plot_methodical_scores: no visible binding for global variable
  ‘meth_site_plot_position’
plot_methodical_scores: no visible binding for global variable
  ‘methodical_score’
plot_methodical_scores: no visible binding for global variable ‘cor’
plot_tmrs: no visible binding for global variable ‘direction’
plot_tmrs: no visible global function definition for ‘setNames’
rapid_cor_test: no visible global function definition for ‘cor’
rapid_cor_test: no visible global function definition for ‘pt’
rapid_cor_test: no visible global function definition for ‘p.adjust’
split_bedgraphs_into_chunks: no visible global function definition for
  ‘%dopar%’
split_bedgraphs_into_chunks: no visible binding for global variable
  ‘column’
split_bedgraphs_into_chunks: no visible binding for global variable
  ‘file_count’
split_bedgraphs_into_chunks: no visible binding for global variable
  ‘bg_file’
split_bedgraphs_into_chunks: no visible global function definition for
  ‘setNames’
split_bedgraphs_into_chunks: no visible global function definition for
  ‘%do%’
split_bedgraphs_into_chunks: no visible binding for global variable
  ‘mg’
split_meth_array_files_into_chunks: no visible binding for global
  variable ‘name’
split_meth_array_files_into_chunks: no visible global function
  definition for ‘%dopar%’
split_meth_array_files_into_chunks: no visible binding for global
  variable ‘column’
split_meth_array_files_into_chunks: no visible binding for global
  variable ‘file_count’
split_meth_array_files_into_chunks: no visible global function
  definition for ‘setNames’
split_meth_array_files_into_chunks: no visible global function
  definition for ‘%do%’
split_meth_array_files_into_chunks: no visible binding for global
  variable ‘pg’
sum_transcript_values_for_genes: no visible global function definition
  for ‘is’
sum_transcript_values_for_genes: no visible binding for global variable
  ‘gene_transcripts’
summarize_region_methylation: no visible global function definition for
  ‘is’
summarize_region_methylation: no visible global function definition for
  ‘seqlevels’
summarize_region_methylation: no visible global function definition for
  ‘%dopar%’
summarize_region_methylation: no visible binding for global variable
  ‘chunk’
summarize_region_methylation: no visible global function definition for
  ‘subsetByOverlaps’
write_chunks_to_hdf5: no visible binding for global variable ‘chunk’
Undefined global functions or variables:
  %do% %dopar% IRanges bg_file chunk colorRampPalette column
  complete.cases cor direction file_count gene_transcripts is
  meth_site_plot_position meth_site_start methodical_score mg name
  overlapsAny p.adjust pg pt queryHits region_type seqlengths seqlevels
  setNames subsetByOverlaps transcript transcript_name transcript_tss
Consider adding
  importFrom("grDevices", "colorRampPalette")
  importFrom("methods", "is")
  importFrom("stats", "complete.cases", "cor", "p.adjust", "pt",
             "setNames")
to your NAMESPACE file (and ensure that your DESCRIPTION Imports field
contains 'methods').
* checking Rd files ... [0s/0s] OK
* checking Rd metadata ... OK
* checking Rd line widths ... NOTE
Rd file 'annotate_meth_site_plot.Rd':
  \examples lines wider than 100 characters:
     methodical::annotate_meth_site_plot(tubb6_correlation_plot, cpg_islands, annotation_plot_height = 0.3)

Rd file 'calculate_meth_site_transcript_cors.Rd':
  \examples lines wider than 100 characters:
     # Load TUBB6 TSS GRanges, RangedSummarizedExperiment with methylation values for CpGs around TUBB6 TSS and TUBB6 transcript counts
     tubb6_cpg_meth_transcript_cors = methodical::calculate_meth_site_transcript_cors(meth_rse = tubb6_meth_rse, 
       transcript_expression_table = tubb6_transcript_counts, tss_gr = tubb6_tss, expand_upstream = 5000, expand_downstream = 5000)

Rd file 'calculate_region_methylation_transcript_cors.Rd':
  \examples lines wider than 100 characters:
     # Load TUBB6 TMRs, RangedSummarizedExperiment with methylation values for CpGs around TUBB6 TSS and TUBB6 transcript counts
       genomic_regions = tubb6_tmrs, genomic_region_names = tubb6_tmrs$tmr_name, meth_rse = tubb6_meth_rse, transcript_table = tubb6_transcr ... [TRUNCATED]

Rd file 'calculate_smoothed_methodical_scores.Rd':
  \examples lines wider than 100 characters:
     smoothed_methodical_scores = methodical::calculate_smoothed_methodical_scores(tubb6_cpg_meth_transcript_cors)

Rd file 'create_random_regions.Rd':
  \examples lines wider than 100 characters:
     random_regions = methodical::create_random_regions(genome = "BSgenome.Hsapiens.UCSC.hg38", n_regions = 10000)

Rd file 'extract_granges_meth_site_values.Rd':
  \examples lines wider than 100 characters:
     test_region_methylation = methodical::extract_granges_meth_site_values(tubb6_meth_rse, genomic_regions = test_region)

Rd file 'extract_meth_sites_from_genome.Rd':
  \examples lines wider than 100 characters:
     arabidopsis_cphpgs = methodical::extract_meth_sites_from_genome("BSgenome.Athaliana.TAIR.TAIR9", pattern = "CHG")

Rd file 'kallisto_index.Rd':
  \examples lines wider than 100 characters:
     download.file("https://ftp.ebi.ac.uk/pub/databases/gencode/Gencode_human/release_44/gencode.v44.transcripts.fa.gz")

Rd file 'liftover_meth_rse.Rd':
  \examples lines wider than 100 characters:
     # Liftover tubb6_meth_rse from hg38 to hg19, keeping only sites that were mapped to CpG sites in hg19

Rd file 'plot_meth_site_values.Rd':
  \examples lines wider than 100 characters:
     methodical::plot_meth_site_values(tubb6_cpg_meth_transcript_cors, column_name = "cor", ylabel = "Spearman Correlation")
       ylabel = "Spearman Correlation", reference_region = attributes(tubb6_cpg_meth_transcript_cors)$tss_range)

Rd file 'plot_methodical_scores.Rd':
  \examples lines wider than 100 characters:
     methodical::plot_methodical_scores(tubb6_cpg_meth_transcript_cors, reference_region = attributes(tubb6_cpg_meth_transcript_cors)$tss_ra ... [TRUNCATED]

Rd file 'plot_tmrs.Rd':
  \examples lines wider than 100 characters:
     tubb6_correlation_plot = methodical::plot_meth_site_values(tubb6_cpg_meth_transcript_cors, column_name = "cor", ylabel = "Spearman Corr ... [TRUNCATED]

Rd file 'sample_meth_sites.Rd':
  \examples lines wider than 100 characters:
     random_cpgs = methodical::sample_meth_sites(tubb6_meth_rse, n_sites = 20, genomic_ranges_filter = mask_ranges, 

Rd file 'summarize_region_methylation.Rd':
  \examples lines wider than 100 characters:
     test_gr = GRanges(c("chr18:12303400-12303500", "chr18:12303600-12303750", "chr18:12304000-12306000"))
     test_gr_methylation = methodical::summarize_region_methylation(tubb6_meth_rse, genomic_regions = test_gr,

These lines will be truncated in the PDF manual.
* checking Rd cross-references ... OK
* checking for missing documentation entries ... OK
* checking for code/documentation mismatches ... OK
* checking Rd \usage sections ... OK
* checking Rd contents ... OK
* checking for unstated dependencies in examples ... OK
* checking contents of ‘data’ directory ... OK
* checking data for non-ASCII characters ... [8s/8s] OK
* checking data for ASCII and uncompressed saves ... OK
* checking files in ‘vignettes’ ... OK
* checking examples ... [168s/186s] ERROR
Running examples in ‘methodical-Ex.R’ failed
The error most likely occurred in:

> base::assign(".ptime", proc.time(), pos = "CheckExEnv")
> ### Name: liftover_meth_rse
> ### Title: Liftover rowRanges of a RangedSummarizedExperiment for
> ###   methylation data from one genome build to another
> ### Aliases: liftover_meth_rse
> 
> ### ** Examples
> 
> # Load sample RangedSummarizedExperiment with CpG methylation data
> data(tubb6_meth_rse, package = "methodical"); tubb6_meth_rse = eval(tubb6_meth_rse)
>   
> # Get CpG sites for hg19
> hg19_cpgs = methodical::extract_meth_sites_from_genome("BSgenome.Hsapiens.UCSC.hg19")
Error in .stopOnAvailablePkg(genome) : 
  BSgenome.Hsapiens.UCSC.hg19 package is not currently installed.
  You first need to install it, which you can do with:
      library(BiocManager)
      install("BSgenome.Hsapiens.UCSC.hg19")
Calls: <Anonymous> ... .getBSgenomeObjectFromInstalledPkgname -> .stopOnAvailablePkg
Execution halted
* checking for unstated dependencies in vignettes ... OK
* checking package vignettes in ‘inst/doc’ ... OK
* checking running R code from vignettes ... SKIPPED
* checking re-building of vignette outputs ... SKIPPED
* checking PDF version of manual ... [3s/3s] OK
* DONE

Status: 1 ERROR, 3 NOTEs
See
  ‘/home/pkgbuild/packagebuilder/workers/jobs/3169/methodical_20231006145408/methodical.Rcheck/00check.log’
for details.





===============================

 BiocCheck('methodical_0.99.0.tar.gz')

===============================

─ BiocCheckVersion: 1.37.16
─ BiocVersion: 3.18
─ Package: methodical
─ PackageVersion: 0.99.0
─ sourceDir: /tmp/RtmpeGomY4/file18a6221eae1c9b/methodical
─ installDir: /tmp/RtmpeGomY4/file18a6222c6249ba
─ BiocCheckDir: /home/pkgbuild/packagebuilder/workers/jobs/3169/methodical_20231006145408/methodical.BiocCheck
─ platform: unix
─ isTarBall: TRUE

* Installing package...
* Checking for deprecated package usage...
* Checking for remote package usage...
* Checking for 'LazyData: true' usage...
* Checking version number...
* Checking for version number mismatch...
* Checking new package version number...
* Checking R version dependency...
    * NOTE: Update R version dependency from 3.5.0 to 4.3.0.
* Checking package size...
    * ERROR: Package tarball exceeds the Bioconductor size requirement.
* Checking individual file sizes...
* Checking biocViews...
* Checking that biocViews are present...
* Checking package type based on biocViews...
    Software
* Checking for non-trivial biocViews...
* Checking that biocViews come from the same category...
* Checking biocViews validity...
* Checking for recommended biocViews...
    * NOTE: Consider adding these automatically suggested biocViews:
      Sequencing, Coverage, GenomeWideAssociation
Search 'biocViews' at https://contributions.bioconductor.org
* Checking build system compatibility...
* Checking for blank lines in DESCRIPTION...
* Checking if DESCRIPTION is well formatted...
* Checking for proper Description: field...
* Checking for whitespace in DESCRIPTION field names...
* Checking that Package field matches directory/tarball name...
* Checking for Version field...
* Checking for valid maintainer...
* Checking License: for restrictive use...
    * NOTE: License 'GPL (>= 3)' unknown; licenses cannot restrict use
* Checking for recommeded fields in DESCRIPTION...
    * NOTE: Provide 'URL' field(s) in DESCRIPTION
* Checking for pinned package versions...
* Checking DESCRIPTION/NAMESPACE consistency...
* Checking .Rbuildignore...
* Checking for stray BiocCheck output folders...
* Checking vignette directory...
* Checking whether vignette is built with 'R CMD build'...
* Checking package installation calls in R code...
* Checking for library/require of methodical...
    * WARNING: Avoid the use of 'library' or 'require' in R code
* Checking coding practice...
    * NOTE: Avoid sapply(); use vapply()
    * NOTE: Avoid 1:...; use seq_len() or seq_along()
    * NOTE: Avoid 'cat' and 'print' outside of 'show' methods
    * NOTE: Avoid using '=' for assignment and use '<-' instead
    * NOTE: Avoid the use of 'paste' in condition signals
* Checking parsed R code in R directory, examples, vignettes...
    * NOTE: Avoid 'suppressWarnings'/'*Messages' if possible (found 4
      times)
* Checking function lengths...
    * NOTE: The recommended function length is 50 lines or less. There
      are 12 functions greater than 50 lines.
* Checking man page documentation...
    * NOTE: Consider adding runnable examples to man pages that
      document exported objects.
    * NOTE: Usage of dontrun{} / donttest{} tags found in man page
      examples. 2% of man pages use at least one of these tags.
    * NOTE: Use donttest{} instead of dontrun{}.
* Checking package NEWS...
* Checking unit tests...
    * NOTE: Consider adding unit tests. We strongly encourage them. See
      https://contributions.bioconductor.org/tests.html
* Checking skip_on_bioc() in tests...
* Checking formatting of DESCRIPTION, NAMESPACE, man pages, R source,
  and vignette source...
    * NOTE: Consider shorter lines; 1068 lines (23%) are > 80
      characters long.
    * NOTE: Consider multiples of 4 spaces for line indents; 1538 lines
      (33%) are not.
    See https://contributions.bioconductor.org/r-code.html
    See styler package: https://cran.r-project.org/package=styler as
      described in the BiocCheck vignette.
* Checking if package already exists in CRAN...
* Checking if new package already exists in Bioconductor...
* Checking for bioc-devel mailing list subscription...
    Maintainer is subscribed to bioc-devel.
* Checking for support site registration...
    Maintainer is registered at support site.
    Package name is in support site watched tags.

─ BiocCheck results ──
1 ERRORS | 1 WARNINGS | 17 NOTES

See the methodical.BiocCheck folder and run
    browseVignettes(package = 'BiocCheck')
for details.

nebbiolo2 BUILD BIN output

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lconway Summary

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Package: methodical
Version: 0.99.0
RVersion: 4.3
BiocVersion: 3.18
BuildCommand: /Library/Frameworks/R.framework/Versions/Current/Resources/bin/R CMD build --keep-empty-dirs --no-resave-data methodical
BuildTime: 0 minutes 40.07 seconds
CheckCommand: BiocCheckGitClone('methodical') && /Library/Frameworks/R.framework/Versions/Current/Resources/bin/R CMD check --no-vignettes --timings --library=/Users/pkgbuild/packagebuilder/workers/jobs/3169/R-libs --install=check:/Users/pkgbuild/packagebuilder/workers/jobs/3169/methodical_20231006145408/methodical.install-out.txt methodical_0.99.0.tar.gz && BiocCheck('methodical_0.99.0.tar.gz', `new-package`=TRUE)
CheckTime: 13 minutes 4.76 seconds
BuildBinCommand: /Users/biocbuild/BBS/utils/build-universal.sh methodical_0.99.0.tar.gz /Library/Frameworks/R.framework/Versions/Current/Resources/bin/R libdir
BuildBinTime: 0 minutes 24.08 seconds
PackageFileSize: 7142.67 KiB
BuildID:: methodical_20231006145408
PreProcessing: Starting Git clone. Installing dependencies. Checking Git Clone. Installing package: methodical. Starting Build package. Starting Check package. Starting Build package.
PostProcessing: Finished Git clone. Package type: Software. Installing dependency status: 0. Checking git clone status: 0. Installing package status: 0. Build Package status: 0. Adding Build Product Information to Database.Checking Package status: 1. Build Package status: 0.

lconway BUILD SRC output

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===============================

 R CMD BUILD

===============================

* checking for file ‘methodical/DESCRIPTION’ ... OK
* preparing ‘methodical’:
* checking DESCRIPTION meta-information ... OK
* installing the package to build vignettes
* creating vignettes ... OK
* checking for LF line-endings in source and make files and shell scripts
* checking for empty or unneeded directories
* looking to see if a ‘data/datalist’ file should be added
  NB: this package now depends on R (>= 3.5.0)
  WARNING: Added dependency on R >= 3.5.0 because serialized objects in
  serialize/load version 3 cannot be read in older versions of R.
  File(s) containing such objects:
    ‘methodical/inst/extdata/tubb6_meth_rse/se.rds’
* building ‘methodical_0.99.0.tar.gz’


lconway CHECK output

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===============================

 BiocCheckGitClone('methodical')

===============================

─ BiocCheckVersion: 1.37.16
─ BiocVersion: 3.18
─ Package: methodical
─ PackageVersion: 0.99.0
─ sourceDir: /Users/pkgbuild/packagebuilder/workers/jobs/3169/methodical_20231006145408/methodical
─ platform: unix
─ isTarBall: FALSE

* Checking valid files...
* Checking for stray BiocCheck output folders...
* Checking for inst/doc folders...
* Checking DESCRIPTION...
* Checking if DESCRIPTION is well formatted...
* Checking for valid maintainer...
* Checking CITATION...

─ BiocCheck results ──
0 ERRORS | 0 WARNINGS | 0 NOTES

For more details, run
    browseVignettes(package = 'BiocCheck')




===============================

 R CMD CHECK

===============================

* using log directory ‘/Users/pkgbuild/packagebuilder/workers/jobs/3169/methodical_20231006145408/methodical.Rcheck’
* using R version 4.3.1 Patched (2023-06-17 r84564)
* using platform: x86_64-apple-darwin20 (64-bit)
* R was compiled by
    Apple clang version 14.0.3 (clang-1403.0.22.14.1)
    GNU Fortran (GCC) 12.2.0
* running under: macOS Monterey 12.6.5
* using session charset: UTF-8
* using option ‘--no-vignettes’
* checking for file ‘methodical/DESCRIPTION’ ... OK
* this is package ‘methodical’ version ‘0.99.0’
* package encoding: UTF-8
* checking package namespace information ... OK
* checking package dependencies ... OK
* checking if this is a source package ... OK
* checking if there is a namespace ... OK
* checking for hidden files and directories ... OK
* checking for portable file names ... OK
* checking for sufficient/correct file permissions ... OK
* checking whether package ‘methodical’ can be installed ... OK
* checking installed package size ... OK
* checking package directory ... OK
* checking for future file timestamps ... OK
* checking ‘build’ directory ... OK
* checking DESCRIPTION meta-information ... OK
* checking top-level files ... OK
* checking for left-over files ... OK
* checking index information ... OK
* checking package subdirectories ... OK
* checking R files for non-ASCII characters ... OK
* checking R files for syntax errors ... OK
* checking whether the package can be loaded ... [5s/5s] OK
* checking whether the package can be loaded with stated dependencies ... [4s/5s] OK
* checking whether the package can be unloaded cleanly ... [5s/5s] OK
* checking whether the namespace can be loaded with stated dependencies ... [4s/4s] OK
* checking whether the namespace can be unloaded cleanly ... [4s/5s] OK
* checking loading without being on the library search path ... [5s/5s] OK
* checking use of S3 registration ... OK
* checking dependencies in R code ... NOTE
Unexported object imported by a ':::' call: ‘HDF5Array:::.serialize_HDF5SummarizedExperiment’
  See the note in ?`:::` about the use of this operator.
* checking S3 generic/method consistency ... OK
* checking replacement functions ... OK
* checking foreign function calls ... OK
* checking R code for possible problems ... [18s/18s] NOTE
annotate_granges: no visible global function definition for ‘is’
annotate_meth_site_plot: no visible global function definition for
  ‘subsetByOverlaps’
annotate_meth_site_plot: no visible global function definition for
  ‘setNames’
annotate_meth_site_plot: no visible global function definition for
  ‘colorRampPalette’
annotate_meth_site_plot: no visible binding for global variable
  ‘region_type’
calculate_meth_site_transcript_cors: no visible global function
  definition for ‘%do%’
calculate_meth_site_transcript_cors: no visible binding for global
  variable ‘chunk’
calculate_meth_site_transcript_cors: no visible global function
  definition for ‘subsetByOverlaps’
calculate_meth_site_transcript_cors: no visible global function
  definition for ‘%dopar%’
calculate_meth_site_transcript_cors: no visible global function
  definition for ‘setNames’
calculate_meth_site_transcript_cors: no visible binding for global
  variable ‘transcript_name’
calculate_meth_site_transcript_cors: no visible binding for global
  variable ‘transcript_tss’
calculate_region_methylation_transcript_cors: no visible binding for
  global variable ‘transcript’
calculate_region_methylation_transcript_cors: no visible global
  function definition for ‘setNames’
calculate_region_methylation_transcript_cors: no visible global
  function definition for ‘p.adjust’
chunk_regions: no visible global function definition for
  ‘subsetByOverlaps’
create_meth_rse_from_hdf5: no visible global function definition for
  ‘setNames’
create_random_regions: no visible global function definition for
  ‘seqlengths’
create_random_regions: no visible global function definition for
  ‘overlapsAny’
expand_granges: no visible global function definition for ‘is’
expand_granges: no visible global function definition for ‘IRanges’
kallisto_quantify: no visible global function definition for ‘setNames’
mask_ranges_in_rse: no visible global function definition for ‘is’
mask_ranges_in_rse: no visible global function definition for
  ‘queryHits’
plot_meth_site_values: no visible global function definition for
  ‘seqlevels’
plot_meth_site_values: no visible global function definition for
  ‘complete.cases’
plot_meth_site_values: no visible binding for global variable
  ‘meth_site_plot_position’
plot_methodical_scores: no visible global function definition for
  ‘seqlevels’
plot_methodical_scores: no visible binding for global variable
  ‘meth_site_start’
plot_methodical_scores: no visible binding for global variable
  ‘meth_site_plot_position’
plot_methodical_scores: no visible binding for global variable
  ‘methodical_score’
plot_methodical_scores: no visible binding for global variable ‘cor’
plot_tmrs: no visible binding for global variable ‘direction’
plot_tmrs: no visible global function definition for ‘setNames’
rapid_cor_test: no visible global function definition for ‘cor’
rapid_cor_test: no visible global function definition for ‘pt’
rapid_cor_test: no visible global function definition for ‘p.adjust’
split_bedgraphs_into_chunks: no visible global function definition for
  ‘%dopar%’
split_bedgraphs_into_chunks: no visible binding for global variable
  ‘column’
split_bedgraphs_into_chunks: no visible binding for global variable
  ‘file_count’
split_bedgraphs_into_chunks: no visible binding for global variable
  ‘bg_file’
split_bedgraphs_into_chunks: no visible global function definition for
  ‘setNames’
split_bedgraphs_into_chunks: no visible global function definition for
  ‘%do%’
split_bedgraphs_into_chunks: no visible binding for global variable
  ‘mg’
split_meth_array_files_into_chunks: no visible binding for global
  variable ‘name’
split_meth_array_files_into_chunks: no visible global function
  definition for ‘%dopar%’
split_meth_array_files_into_chunks: no visible binding for global
  variable ‘column’
split_meth_array_files_into_chunks: no visible binding for global
  variable ‘file_count’
split_meth_array_files_into_chunks: no visible global function
  definition for ‘setNames’
split_meth_array_files_into_chunks: no visible global function
  definition for ‘%do%’
split_meth_array_files_into_chunks: no visible binding for global
  variable ‘pg’
sum_transcript_values_for_genes: no visible global function definition
  for ‘is’
sum_transcript_values_for_genes: no visible binding for global variable
  ‘gene_transcripts’
summarize_region_methylation: no visible global function definition for
  ‘is’
summarize_region_methylation: no visible global function definition for
  ‘seqlevels’
summarize_region_methylation: no visible global function definition for
  ‘%dopar%’
summarize_region_methylation: no visible binding for global variable
  ‘chunk’
summarize_region_methylation: no visible global function definition for
  ‘subsetByOverlaps’
write_chunks_to_hdf5: no visible binding for global variable ‘chunk’
Undefined global functions or variables:
  %do% %dopar% IRanges bg_file chunk colorRampPalette column
  complete.cases cor direction file_count gene_transcripts is
  meth_site_plot_position meth_site_start methodical_score mg name
  overlapsAny p.adjust pg pt queryHits region_type seqlengths seqlevels
  setNames subsetByOverlaps transcript transcript_name transcript_tss
Consider adding
  importFrom("grDevices", "colorRampPalette")
  importFrom("methods", "is")
  importFrom("stats", "complete.cases", "cor", "p.adjust", "pt",
             "setNames")
to your NAMESPACE file (and ensure that your DESCRIPTION Imports field
contains 'methods').
* checking Rd files ... [0s/0s] OK
* checking Rd metadata ... OK
* checking Rd line widths ... NOTE
Rd file 'annotate_meth_site_plot.Rd':
  \examples lines wider than 100 characters:
     methodical::annotate_meth_site_plot(tubb6_correlation_plot, cpg_islands, annotation_plot_height = 0.3)

Rd file 'calculate_meth_site_transcript_cors.Rd':
  \examples lines wider than 100 characters:
     # Load TUBB6 TSS GRanges, RangedSummarizedExperiment with methylation values for CpGs around TUBB6 TSS and TUBB6 transcript counts
     tubb6_cpg_meth_transcript_cors = methodical::calculate_meth_site_transcript_cors(meth_rse = tubb6_meth_rse, 
       transcript_expression_table = tubb6_transcript_counts, tss_gr = tubb6_tss, expand_upstream = 5000, expand_downstream = 5000)

Rd file 'calculate_region_methylation_transcript_cors.Rd':
  \examples lines wider than 100 characters:
     # Load TUBB6 TMRs, RangedSummarizedExperiment with methylation values for CpGs around TUBB6 TSS and TUBB6 transcript counts
       genomic_regions = tubb6_tmrs, genomic_region_names = tubb6_tmrs$tmr_name, meth_rse = tubb6_meth_rse, transcript_table = tubb6_transcr ... [TRUNCATED]

Rd file 'calculate_smoothed_methodical_scores.Rd':
  \examples lines wider than 100 characters:
     smoothed_methodical_scores = methodical::calculate_smoothed_methodical_scores(tubb6_cpg_meth_transcript_cors)

Rd file 'create_random_regions.Rd':
  \examples lines wider than 100 characters:
     random_regions = methodical::create_random_regions(genome = "BSgenome.Hsapiens.UCSC.hg38", n_regions = 10000)

Rd file 'extract_granges_meth_site_values.Rd':
  \examples lines wider than 100 characters:
     test_region_methylation = methodical::extract_granges_meth_site_values(tubb6_meth_rse, genomic_regions = test_region)

Rd file 'extract_meth_sites_from_genome.Rd':
  \examples lines wider than 100 characters:
     arabidopsis_cphpgs = methodical::extract_meth_sites_from_genome("BSgenome.Athaliana.TAIR.TAIR9", pattern = "CHG")

Rd file 'kallisto_index.Rd':
  \examples lines wider than 100 characters:
     download.file("https://ftp.ebi.ac.uk/pub/databases/gencode/Gencode_human/release_44/gencode.v44.transcripts.fa.gz")

Rd file 'liftover_meth_rse.Rd':
  \examples lines wider than 100 characters:
     # Liftover tubb6_meth_rse from hg38 to hg19, keeping only sites that were mapped to CpG sites in hg19

Rd file 'plot_meth_site_values.Rd':
  \examples lines wider than 100 characters:
     methodical::plot_meth_site_values(tubb6_cpg_meth_transcript_cors, column_name = "cor", ylabel = "Spearman Correlation")
       ylabel = "Spearman Correlation", reference_region = attributes(tubb6_cpg_meth_transcript_cors)$tss_range)

Rd file 'plot_methodical_scores.Rd':
  \examples lines wider than 100 characters:
     methodical::plot_methodical_scores(tubb6_cpg_meth_transcript_cors, reference_region = attributes(tubb6_cpg_meth_transcript_cors)$tss_ra ... [TRUNCATED]

Rd file 'plot_tmrs.Rd':
  \examples lines wider than 100 characters:
     tubb6_correlation_plot = methodical::plot_meth_site_values(tubb6_cpg_meth_transcript_cors, column_name = "cor", ylabel = "Spearman Corr ... [TRUNCATED]

Rd file 'sample_meth_sites.Rd':
  \examples lines wider than 100 characters:
     random_cpgs = methodical::sample_meth_sites(tubb6_meth_rse, n_sites = 20, genomic_ranges_filter = mask_ranges, 

Rd file 'summarize_region_methylation.Rd':
  \examples lines wider than 100 characters:
     test_gr = GRanges(c("chr18:12303400-12303500", "chr18:12303600-12303750", "chr18:12304000-12306000"))
     test_gr_methylation = methodical::summarize_region_methylation(tubb6_meth_rse, genomic_regions = test_gr,

These lines will be truncated in the PDF manual.
* checking Rd cross-references ... OK
* checking for missing documentation entries ... OK
* checking for code/documentation mismatches ... OK
* checking Rd \usage sections ... OK
* checking Rd contents ... OK
* checking for unstated dependencies in examples ... OK
* checking contents of ‘data’ directory ... OK
* checking data for non-ASCII characters ... [6s/6s] OK
* checking data for ASCII and uncompressed saves ... OK
* checking files in ‘vignettes’ ... OK
* checking examples ... [10m/11m] OK
Examples with CPU (user + system) or elapsed time > 5s
                                  user system elapsed
make_meth_rse_from_bedgraphs   286.554 30.948 357.887
extract_meth_sites_from_genome  89.469  8.569 101.137
liftover_meth_rse               87.770  9.429 117.419
make_meth_rse_from_array_files  10.147  0.379  10.550
annotate_meth_site_plot          6.938  0.465  24.873
summarize_region_methylation     5.735  0.038   5.785
* checking for unstated dependencies in vignettes ... OK
* checking package vignettes in ‘inst/doc’ ... OK
* checking running R code from vignettes ... SKIPPED
* checking re-building of vignette outputs ... SKIPPED
* checking PDF version of manual ... [6s/7s] OK
* DONE

Status: 3 NOTEs
See
  ‘/Users/pkgbuild/packagebuilder/workers/jobs/3169/methodical_20231006145408/methodical.Rcheck/00check.log’
for details.


 WARNING: R CMD check exceeded 10 min requirement






===============================

 BiocCheck('methodical_0.99.0.tar.gz')

===============================

─ BiocCheckVersion: 1.37.16
─ BiocVersion: 3.18
─ Package: methodical
─ PackageVersion: 0.99.0
─ sourceDir: /var/folders/db/d7_0z9ss4n3692ppdmx9hlgr0000gv/T//Rtmp6catHD/file93ce1e8fd01d/methodical
─ installDir: /var/folders/db/d7_0z9ss4n3692ppdmx9hlgr0000gv/T//Rtmp6catHD/file93ce26cc9dd3
─ BiocCheckDir: /Users/pkgbuild/packagebuilder/workers/jobs/3169/methodical_20231006145408/methodical.BiocCheck
─ platform: unix
─ isTarBall: TRUE

* Installing package...
* Checking for deprecated package usage...
* Checking for remote package usage...
* Checking for 'LazyData: true' usage...
* Checking version number...
* Checking for version number mismatch...
* Checking new package version number...
* Checking R version dependency...
    * NOTE: Update R version dependency from 3.5.0 to 4.3.0.
* Checking package size...
    * ERROR: Package tarball exceeds the Bioconductor size requirement.
* Checking individual file sizes...
* Checking biocViews...
* Checking that biocViews are present...
* Checking package type based on biocViews...
    Software
* Checking for non-trivial biocViews...
* Checking that biocViews come from the same category...
* Checking biocViews validity...
* Checking for recommended biocViews...
    * NOTE: Consider adding these automatically suggested biocViews:
      Sequencing, Coverage, GenomeWideAssociation
Search 'biocViews' at https://contributions.bioconductor.org
* Checking build system compatibility...
* Checking for blank lines in DESCRIPTION...
* Checking if DESCRIPTION is well formatted...
* Checking for proper Description: field...
* Checking for whitespace in DESCRIPTION field names...
* Checking that Package field matches directory/tarball name...
* Checking for Version field...
* Checking for valid maintainer...
* Checking License: for restrictive use...
    * NOTE: License 'GPL (>= 3)' unknown; licenses cannot restrict use
* Checking for recommeded fields in DESCRIPTION...
    * NOTE: Provide 'URL' field(s) in DESCRIPTION
* Checking for pinned package versions...
* Checking DESCRIPTION/NAMESPACE consistency...
* Checking .Rbuildignore...
* Checking for stray BiocCheck output folders...
* Checking vignette directory...
* Checking whether vignette is built with 'R CMD build'...
* Checking package installation calls in R code...
* Checking for library/require of methodical...
    * WARNING: Avoid the use of 'library' or 'require' in R code
* Checking coding practice...
    * NOTE: Avoid sapply(); use vapply()
    * NOTE: Avoid 1:...; use seq_len() or seq_along()
    * NOTE: Avoid 'cat' and 'print' outside of 'show' methods
    * NOTE: Avoid using '=' for assignment and use '<-' instead
    * NOTE: Avoid the use of 'paste' in condition signals
* Checking parsed R code in R directory, examples, vignettes...
    * NOTE: Avoid 'suppressWarnings'/'*Messages' if possible (found 4
      times)
* Checking function lengths...
    * NOTE: The recommended function length is 50 lines or less. There
      are 12 functions greater than 50 lines.
* Checking man page documentation...
    * NOTE: Consider adding runnable examples to man pages that
      document exported objects.
    * NOTE: Usage of dontrun{} / donttest{} tags found in man page
      examples. 2% of man pages use at least one of these tags.
    * NOTE: Use donttest{} instead of dontrun{}.
* Checking package NEWS...
* Checking unit tests...
    * NOTE: Consider adding unit tests. We strongly encourage them. See
      https://contributions.bioconductor.org/tests.html
* Checking skip_on_bioc() in tests...
* Checking formatting of DESCRIPTION, NAMESPACE, man pages, R source,
  and vignette source...
    * NOTE: Consider shorter lines; 1068 lines (23%) are > 80
      characters long.
    * NOTE: Consider multiples of 4 spaces for line indents; 1538 lines
      (33%) are not.
    See https://contributions.bioconductor.org/r-code.html
    See styler package: https://cran.r-project.org/package=styler as
      described in the BiocCheck vignette.
* Checking if package already exists in CRAN...
* Checking if new package already exists in Bioconductor...
* Checking for bioc-devel mailing list subscription...
    Maintainer is subscribed to bioc-devel.
* Checking for support site registration...
    Maintainer is registered at support site.
    Package name is in support site watched tags.

─ BiocCheck results ──
1 ERRORS | 1 WARNINGS | 17 NOTES

See the methodical.BiocCheck folder and run
    browseVignettes(package = 'BiocCheck')
for details.

lconway BUILD BIN output

[top]

===============================

 R CMD BUILD

===============================

>>>>>>> 
>>>>>>> INSTALLATION WITH 'R CMD INSTALL --preclean --no-multiarch --library=libdir methodical_0.99.0.tar.gz'
>>>>>>> 

* installing *source* package ‘methodical’ ...
** using staged installation
** R
** data
** inst
** byte-compile and prepare package for lazy loading
** help
*** installing help indices
** building package indices
** installing vignettes
** testing if installed package can be loaded from temporary location
** testing if installed package can be loaded from final location
** testing if installed package keeps a record of temporary installation path
* DONE (methodical)